MedImmune Expands Anti-Interferon-Alpha Program By Initiating Phase 1 Trial In Patients With Psoriasis
MedImmune, Inc. (Nasdaq: MEDI) today announced that it has initiated a Phase 1 trial with its monoclonal antibody (MAb) targeting interferon-alpha, known as MEDI-545, in patients with psoriasis. Signaling an expanded focus on the role of interferons in inflammatory diseases, the psoriasis trial marks a second clinical study underway with MEDI-545, which is also being evaluated in an ongoing Phase 1 trial in patients with systemic lupus erythematosus (SLE or lupus).
Medicalnewstoday.com 4h and 29m ago

Medarex Announces Initiation Of Phase I Clinical Trial For The Treatment Of Psoriasis
Medarex, Inc. (Nasdaq: MEDX) announced today that its partner MedImmune, Inc. has initiated a Phase I clinical trial of MEDI-545 for the potential treatment of psoriasis. MEDI-545 is a fully human antibody generated by Medarex's UltiMAb Human Antibody Development System(R). The Phase I dose-escalation trial for the treatment of psoriasis is expected to be conducted at three sites in North America.
Medicalnewstoday.com 4h and 29m ago

Canker Sores: Patch May Help Heal
Title: Canker Sores: Patch May Help HealCategory: Health NewsCreated: 3/23/2007Last Editorial Review: 3/23/2007
MedicineNet Fri, 23 Mar 2007 00:00:00 PDT

Juvenile Arthritis (Juvenile Rheumatoid Arthritis)
Title: Juvenile Arthritis (Juvenile Rheumatoid Arthritis)Category: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 3/22/2007
MedicineNet Thu, 22 Mar 2007 00:00:00 PDT

Pain Therapeutics Cleared To Initiate Phase I Study In Metastatic Melanoma
Pain Therapeutics, Inc. (Nasdaq: PTIE) announced today it has received approval from the Ministry of Health in Israel to begin human testing of a new treatment for metastatic melanoma, a deadly form of skin cancer. Pain Therapeutics' initial Phase I study is designed to evaluate the pharmacokinetics of a proprietary radio-labeled monoclonal antibody in patients diagnosed with metastatic melanoma.
Medicalnewstoday.com Wed, 21 Mar 2007 00:00:00 PDT

Cellular 'SOS' Signal In Response To UV Skin Damage Discovered By UNC Scientists
New research from the University of North Carolina at Chapel Hill School of Medicine has identified two proteins that may help protect against skin cancer.The study, which appears in the advance online edition of the journal Molecular and Cellular Biology, indicates that two proteins, named Timeless and Tipin, form a complex that regulates the rate at which DNA is replicated after exposure to ultraviolet radiation.
Medicalnewstoday.com Tue, 20 Mar 2007 04:00:00 PDT

Smoking May Increase Body Wrinkles
Title: Smoking May Increase Body WrinklesCategory: Health NewsCreated: 3/20/2007Last Editorial Review: 3/20/2007
MedicineNet Tue, 20 Mar 2007 00:00:00 PDT

Treating Psoriasis: The Pharmacogenomic Approach
This study published in the journal "Dermatology" shows that investigating individual gene characteristics of patients with psoriasis improves the possibilities of pharmacotherapy using pharmacogenomic approaches, which in future could be further stratified according to the subtypes of psoriasis.A total of 293 patients with plaque psoriasis, 82 patients with psoriasis guttata and 202 control subjects were enrolled in this study.
Medicalnewstoday.com Sun, 18 Mar 2007 00:00:00 PDT

Hyperhidrosis
Title: HyperhidrosisCategory: Diseases and ConditionsCreated: 10/7/2004Last Editorial Review: 3/16/2007
MedicineNet Fri, 16 Mar 2007 00:00:00 PDT

Potetial New Drug Targets Could Stem From Molecular Differences Between Early And Advanced Melanomas
The cell-signaling molecule Akt is a primary trigger that leads malignant melanomas on the skin's surface to begin growing vertically beneath the skin and turn into deadly invasive cancers, scientists have found. Understanding this key molecular difference between radial melanomas that spread on the surface of the skin and melanomas that grow vertically and invasively could provide new targets for the development of drugs to treat individuals with advanced stage melanomas.
Medicalnewstoday.com Thu, 15 Mar 2007 21:00:00 PDT

Tanning May Be Addictive
Title: Tanning May Be AddictiveCategory: Health NewsCreated: 3/15/2007Last Editorial Review: 3/15/2007
MedicineNet Thu, 15 Mar 2007 00:00:00 PDT

Lev Pharmaceuticals Reports Positive Results In Pivotal Phase III Trial For Hereditary Angioedema
Lev Pharmaceuticals, Inc. (Lev) (OTC Bulletin Board: LEVP) today announced positive results from its pivotal U.S. Phase III trial of C1-esterase inhibitor (C1-INH) for the acute treatment of hereditary angioedema (HAE).
Medicalnewstoday.com Thu, 15 Mar 2007 00:00:00 PDT

New Study Indicates Tanning May Be Addictive
Despite repeated health warnings about the dangers of tanning from sunlight and artificial light sources, there are still those whose mantra "bronzed is beautiful" remains unshaken. Dermatologists have long suspected that some people may be addicted to tanning -- similar to addictions to drugs or alcohol -- and refuse to alter their behaviors, even knowing they have an increased risk of developing skin cancer.
Medicalnewstoday.com Tue, 13 Mar 2007 00:00:00 PDT

Cellular Matrices And Tissue Scaffolds Providing An Evolving Solution To Refractory Wounds
Wound care treatments that mimic the body's natural physiology and/or regenerative pathways - technologies that include tissue-engineered skin substitutes, regeneration matrices, and biologically active cellular therapies - are making strides in clinical trial settings and are on track to change the way difficult-to-treat wounds are managed.
Medicalnewstoday.com Mon, 12 Mar 2007 10:00:00 PDT

'Guardian Of The Genome' Protein Found To Underlie Skin Tanning And Influence Human Fondness For Sunshine
A protein known as the "master watchman of the genome" for its ability to guard against cancer-causing DNA damage has been found to provide an entirely different level of cancer protection: By prompting the skin to tan in response to ultraviolet light from the sun, it deters the development of melanoma skin cancer, the fastest-increasing form of cancer in the world.
Medicalnewstoday.com Sun, 11 Mar 2007 03:00:00 PDT

Stress Makes Teen Acne Worse
Title: Stress Makes Teen Acne WorseCategory: Health NewsCreated: 3/8/2007Last Editorial Review: 3/8/2007
MedicineNet Thu, 8 Mar 2007 00:00:00 PDT

Link Found Between Teens' Stress Levels And Acne Severity
The largest study ever conducted on acne and stress reveals that teenagers who were under high levels of stress were 23 percent more likely to have increased acne severity, according to researchers from Wake Forest University School of Medicine and colleagues."Acne significantly affects physical and psychosocial well-being, so it is important to understand the interplay between the factors that exacerbate acne," said Gil Yosipovitch, M.D.
Medicalnewstoday.com Thu, 08 Mar 2007 00:00:00 PDT

Eczema: Dry Hands May Be Sign of Eczema
Title: Eczema: Dry Hands May Be Sign of EczemaCategory: Doctor's ViewsCreated: 1/24/2005Last Editorial Review: 3/5/2007
MedicineNet Mon, 5 Mar 2007 00:00:00 PDT

Questions and Answers About Acne
This fact sheet contains general information about acne. It describes what acne is and how it develops, the causes of acne, and the treatment options for various forms of acne. Information is also provided on caring for the skin. If you have further questions after reading this booklet, you may wish to discuss them with your doctor.
acneplace.com

What Is Acne?
Acne is a disorder resulting from the action of hormones on the skin's oil glands (sebaceous glands), which leads to plugged pores and outbreaks of lesions commonly called pimples or zits. Acne lesions usually occur on the face, neck, back, chest, and shoulders. Nearly 17 million people in the United States have acne, making it the most common skin disease. Although acne is not a serious health threat, severe acne can lead to disfiguring, permanent scarring, which can be upsetting to people who are affected by the disorder.
acneplace.com

How Does Acne Develop?
Doctors describe acne as a disease of the pilosebaceous units (PSUs). Found over most of the body, PSUs consist of a sebaceous gland connected to a canal, called a follicle, that contains a fine hair (see "Normal Pilosebaceous Unit" diagram, below). These units are most numerous on the face, upper back, and chest. The sebaceous glands make an oily substance called sebum that normally empties onto the skin surface through the opening of the follicle, commonly called a pore. Cells called keratinocytes line the follicle.
acneplace.com

What Causes Acne?
The exact cause of acne is unknown, but doctors believe it results from several related factors. One important factor is an increase in hormones called androgens (male sex hormones). These increase in both boys and girls during puberty and cause the sebaceous glands to enlarge and make more sebum. Hormonal changes related to pregnancy or starting or stopping birth control pills can also cause acne.
acneplace.com

Myths About the Causes of Acne
There are many myths about what causes acne. Chocolate and greasy foods are often blamed, but foods seem to have little effect on the development and course of acne in most people. Another common myth is that dirty skin causes acne; however, blackheads and other acne lesions are not caused by dirt. Finally, stress does not cause acne.
acneplace.com

Who Gets Acne?
People of all races and ages get acne. It is most common in adolescents and young adults. Nearly 85 percent of people between the ages of 12 and 24 develop the disorder. For most people, acne tends to go away by the time they reach their thirties; however, some people in their forties and fifties continue to have this skin problem
acneplace.com

Duct Tape the Same as Doing Nothing for Warts
A recent study by Dutch researchers compared using duct tape vs. a corn pad that does not touch the wart (placebo) to treat warts and found that there was no...
z.about.com

Stratum Corneum Anatomy - The Key to Healthy, Attractive Skin
The stratum corneum is the outermost of the 5 layers of the epidermis and is largely responsible for the vital barrier function of the skin. These illustrations will take you...
z.about.com

Treatments for Cold Sores
There are several effective treatments for cold sores. This article discusses FDA-approved treatments for cold sores and antiviral medications that may be prescribed for cold sores "off-label."...
z.about.com

The Science of Botox®
Botox® was the number one non-surgical cosmetic procedure performed in 2004. Even though these injections are so popular, there are still misconceptions about how Botox® works. Find out more about...
z.about.com

What Causes Wrinkles
Wrinkles are caused by many factors as we age. Find out more about the major causes of wrinkles including normal aging, sun effects, free radical damage, and others. ...
z.about.com

Normal Skin is Teeming with Bacteria
Using a powerful new molecular method, researchers have found evidence for 182 species of bacteria in normal skin. Reasearchers took samples of forearm skin from six people, three men...
z.about.com


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